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                科技服务 > PCR芯片实验服务 > mTOR信号通路PCR芯片 mTOR Signaling PCR Array

                mTOR信号通路PCR芯片 mTOR Signaling PCR Array

                mTOR信号通路PCR芯片mTOR Signaling PCR Array
                运费 ¥0.00
                (库存 9999 件)
                地区:上海
                简介:上海
                提供商:SABio
                服务名称:PCR芯片
                类mTOR信号通路PCR芯片可用于研究mTOR信号通路中的84个关键基因的◥表达。mTOR是一类丝氨酸/酪氨酸蛋白激酶,整合了来自各方面的信】号(如营养,荷尔蒙,生长因子以及细胞压力等)来调节细胞的生⊙长,代谢以及生存。mTOR激酶可以形成两类蛋白复合物mTORC1 和mTORC1。 mTORC1调控多◣个细胞生物合成过程(蛋白≡合成细胞周期进程,细胞生长以及〇增殖)。mTORC2能激活AKT,对于※细胞的增殖,迁移和存活很▂重要。该芯片@中包含mTORC1和mTORC2复合物中的成员蛋◤白基因,调控mTOR反应的因子,及受mTOR调控下游∮基因。利◆用实时定量PCR,研究者可以方便并且可∴信地对与mTOR相关的基因进行同时检测╱。
                 
                ProductSpeciesTechnologyCat. No.
                mTOR Signaling PCR ArrayHumanGene ExpressionPAHS-098Z
                mTOR Signaling PCR ArrayMouseGene ExpressionPAMM-098Z
                mTOR Signaling PCR ArrayRatGene ExpressionPARN-098Z
                mTOR Signaling PCR ArrayZebrafishGene ExpressionPAZF-098Z
                mTOR Signaling PCR ArrayChinese HamsterGene ExpressionPAJJ-098Z
                mTOR Complexes: mTORC1: MLST8, MTOR, RPTOR. mTORC2: MLST8, MAPKAP1 (SIN1), MTOR, RICTOR. mTOR Upstream Regulators: mTORC1 Positive Regulators: AKT1, AKT2, AKT3, HRAS, IGF1, IKBKB, INS, INSR, IRS1, MAPK1, MAPK3, PDPK1, PIK3C3, PIK3CA, PIK3CB, PIK3CD, PIK3CG, PLD1, PLD2, RHEB, RPS6KA1, RPS6KA2, RPS6KA5, RRAGA, RRAGB, RRAGC, RRAGD, TELO2. mTORC2 Positive Regulators: AKT1, AKT2, AKT3, MAPK1, MAPK3, PDPK1, PIK3C3 (VPS34), PIK3CA, PIK3CB, PIK3CD, PIK3CG, RHEB,RPS6KA1, RPS6KA2, RPS6KA5. mTORC1 Negative Regulators: AKT1S1 (PRAS40), CAB39, CAB39L, DDIT4, DDIT4L, DEPTOR, FKBP1A (FKBP12), FKBP8, IGFBP3, PRKAA1 (AMPK), PRKAA2, PRKAB1, PRKAB2, PRKAG1, PRKAG2, PRKAG3, PTEN, STK11 (LKB1), STRADB, TP53, TSC1, TSC2, YWHAQ (14-3-3θ). mTORC2 Negative Regulators: CAB39, CAB39L, DDIT4 (REDD1), DDIT4L (REDD2), DEPTOR, PRKAA1 (AMPK), PRKAA2, PRKAB1, PRKAB2, PRKAG1, PRKAG2, PRKAG3, STK11 (LKB1), STRADB, TSC1, TSC2. mTOR Downstream Effectors: mTORC1 Positive Regulation: CHUK (IKKa), EIF4B, EIF4E, HIF1A, IKBKB, RPS6, RPS6KB1, RPS6KB2, TP53, VEGFA, VEGFB, VEGFC. mTORC2 Positive Regulation: AKT1, CDC42, GSK3B, HSPA4, ILK, MYO1C, PRKCA, PRKCB, PRKCE, PRKCG, RHOA, RPS6KB1, SGK1. mTORC1 Negative Regulation: EIF4EBP1, EIF4EBP2, PPP2CA, PPP2R2B, PPP2R4, TP53, ULK1, ULK2. Cellular Processes: Amino Acid Response: PIK3C3 (VPS34), RRAGA, RRAGB, RRAGC, RRAGD. Angiogenesis: CHUK (IKKa), DDIT4 (REDD1), DDIT4L (REDD2), HIF1A, IKBKB, VEGFA, VEGFB, VEGFC. Autophagy: PIK3C3 (VPS34), ULK1, ULK2. Cytoskeletal Organization: CDC42, PRKCA, PRKCB, PRKCE, PRKCG, RHOA. Growth Factor Response: HRAS, IGF1, IGFBP3, MAPK1, MAPK3, RPS6KA1, RPS6KA2, RPS6KA5. Energy Stress: PRKAA1 (AMPK), PRKAA2, PRKAB1, PRKAB2, PRKAG1, PRKAG2, PRKAG3. Insulin Signaling: AKT1, AKT2, AKT3, INS, INSR, IRS1, PDPK1, PIK3CA, PIK3CB, PIK3CD, PIK3CG, TP53. Lipid Metabolism: PLD1, PLD2. Translation: EIF4B, EIF4E, EIF4EBP1, EIF4EBP2, PPP2CA, PPP2R2B, PPP2R4, RPS6, RPS6KA1, RPS6KA2, RPS6KA5, RPS6KB1, RPS6KB2.


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