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                科技服务 > PCR芯片实验服务 > 细胞凋亡基因芯片 Apoptosis PCR Array

                细胞凋亡基因芯片 Apoptosis PCR Array

                细胞凋亡基因芯片Apoptosis PCR Array
                运费 ¥0.00
                (库存 9999 件)
                服务名称:细胞凋亡基因芯片(Apoptosis)
                提供商:SABiosciences
                地区:美国
                简介:Apoptosis PCR芯片
                Apoptosis PCR Array
                Apoptosis PCR Array 96HT凋亡PCR芯片96孔板
                Apoptosis PCR ArrayHumanGene ExpressionPAHS-012Z
                Apoptosis PCR ArrayHumanGene Expression 384HTPAHS-3012Z
                Apoptosis PCR ArrayMouseGene ExpressionPAMM-012Z
                Apoptosis PCR ArrayMouseGene Expression 384HTPAMM-3012Z
                Apoptosis PCR ArrayRatGene ExpressionPARN-012Z
                Apoptosis PCR ArrayRatGene Expression 384HTPARN-3012Z
                Apoptosis PCR ArrayRhesus MacaqueGene ExpressionPAQQ-012Z
                Apoptosis PCR ArrayChickenGene ExpressionPAGG-012Z
                Apoptosis PCR ArrayPigGene ExpressionPASS-012Z
                 
                凋亡PCR芯片可用于研♂究参与细胞程序性死亡的84个关键基因的表达。细胞凋亡在正常生物过程中发挥重要作用,如分化、发育和◥体内平衡。应激反应,如热休克、缺血、非折叠蛋白和病毒感↘染,会引起细胞严重受损♀甚至细胞凋亡。细胞凋亡经常导致不可控的细胞生长,如肿瘤形成和癌症;同时↑肿瘤坏死因子(TNF)受体也会通过激◣活FADD和其他死亡受体蛋白引起凋亡。这一芯片包含∏了TNF配体及』受体、bcl-2、半胱天冬酶、IAP、TRAF、CARD、死亡域、死亡▓效应域、CIDE家族,以及参与p53和DNA损伤通路的基因。研究这些基因的表达有助于确定在生物模型和细胞模型中的细胞机制。通过实时定量PCR的方法,研究者即能够利用该芯片简单可靠地同时检测细胞凋亡相关基因的表达。
                 
                基因列表:
                Induction of Apoptosis:
                Death Domain Receptors: CRADD, FADD, TNF, TNFRSF10B (DR5).
                DNA Damage: ABL1, CIDEA, CIDEB, TP53, TP73.
                Extracellular Signals: CFLAR (CASPER), DAPK1, TNFRSF25 (DR3).
                Other: BAD, BAK1, BAX, BCL10, BCL2L11, BID, BIK, BNIP3, BNIP3L, CASP1 (ICE), CASP10 (MCH4), CASP14, CASP2, CASP3, CASP4, CASP6, CASP8, CD27 (TNFRSF7), CD70 (TNFSF7), CYCS, DFFA, DIABLO (SMAC), FAS (TNFRSF6), FASLG (TNFSF6), GADD45A, HRK, LTA (TNFB), NOD1 (CARD4), PYCARD (TMS1/ASC), TNFRSF10A, TNFRSF9, TNFSF10 (TRAIL), TNFSF8, TP53BP2, TRADD, TRAF3.
                Anti-Apoptosis: AKT1, BAG1, BAG3, BAX, BCL2, BCL2A1 (Bfl-1/A1), BCL2L1 (BCL-X), BCL2L10, BCL2L2, BFAR, BIRC3 (c-IAP1), BIRC5, BIRC6, BNIP2, BNIP3, BNIP3L, BRAF, CD27 (TNFRSF7), CD40LG (TNFSF5), CFLAR (CASPER), DAPK1, FAS (TNFRSF6), HRK, IGF1R, IL10, MCL1, NAIP (BIRC1), NFKB1, NOL3, RIPK2, TNF, XIAP (BIRC4).
                Regulation of Apoptosis:
                Negative Regulation: BAG1, BAG3, BCL10, BCL2, BCL2A1 (Bfl-1/A1), BCL2L1 (BCL-X), BCL2L10, BCL2L2, BFAR, BIRC2 (c-IAP2), BIRC3 (c-IAP1), BIRC6, BNIP2, BNIP3, BNIP3L, BRAF, CASP3, CD27 (TNFRSF7), CD40LG (TNFSF5), CFLAR (CASPER), CIDEA, DAPK1, DFFA, FAS (TNFRSF6), IGF1R, MCL1, NAIP (BIRC1), NOL3, TP53, TP73, XIAP (BIRC4).
                Positive Regulation: ABL1, AKT1, BAD, BAK1, BAX, BCL2L11, BID, BIK, BNIP3, BNIP3L, CASP1 (ICE), CASP10 (MCH4), CASP14, CASP2, CASP4, CASP6, CASP8, CD40 (TNFRSF5), CD70 (TNFSF7), CIDEB, CRADD, FADD, FASLG (TNFSF6), HRK, LTA (TNFB), LTBR, NOD1 (CARD4), PYCARD (TMS1/ASC), RIPK2, TNF, TNFRSF10A, TNFRSF10B (DR5), TNFRSF25 (DR3), TNFRSF9, TNFSF10 (TRAIL), TNFSF8, TP53, TP53BP2, TRADD, TRAF2, TRAF3.
                DEATH Domain Proteins: CRADD, DAPK1, FADD, TNFRSF10A, TNFRSF10B (DR5), TNFRSF11B, TNFRSF1A, TNFRSF1B, TNFRSF21, TNFRSF25 (DR3), TRADD.
                Caspases and Regulators: 
                Caspases: CASP1 (ICE), CASP10 (MCH4), CASP14, CASP2, CASP3, CASP4, CASP5, CASP6, CASP7, CASP8, CASP9, CFLAR (CASPER), CRADD, PYCARD (TMS1/ASC).
                Caspase Activators: AIFM1 (PDCD8), APAF1, BAX, BCL2L10, CASP1 (ICE), CASP9, NOD1 (CARD4), PYCARD (TMS1/ASC), TNFRSF10A, TNFRSF10B (DR5), TP53. 

                英拜为您提供细胞凋亡PCR芯片技术服务,您只需提供样品,我们就可以为您完成全部实验,并提供包括实验方法、实验数据与图表的详细实验报告。


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